Till now, it is known that obese people are prone to Diabetes and cardiac disorders. Now in according to a new research, scientists found a correlation between the body shape and the risk of Diabetes and Cardiac diseases.
Scientists say that the location where you gain excess weight determines the risk of Type II Diabetes. Scientists from Massachusetts General Hospital (MGH) in the US found that having an Apple-shaped figure increase the risk of Diabetes and coronary heart diseases.
Apple-shaped people tend to gain weight around their tummy rather than their thighs or hips. Researchers also found out 48 gene variants responsible for the person’s waist-to-hip ratio. These were calibrated to find out the abdominal adiposity and then the genetic risk score.
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The genetic risk score was then applied to 4,00,000 people involved in the previous study. Using the data, researchers found that the genetic risk score is linked to the increases in the incidence of type 2 diabetes and coronary heart disease, along with increases in blood lipids, blood glucose and systolic blood pressure.
People vary in their distribution of body fat, some have fat in their belly, which is called abdominal adiposity. This has been correlated to with cardiometabolic disorders.
Scientists are conducting research to identify individual genes that could be targeted to improve body fat distribution ultimately reducing these risks.
The article was originally published in the journal JAMA, titled Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease
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